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In this issue of PAIN , Letzen et al. examine the test–retest reliability of functional magnetic resonance imaging (fMRI) connectivity (fcMRI) measures and self-reported pain during pain stimulation and show that fcMRI measures are less reliable than self-reported pain. This study is a valuable endeavor, and as we move toward developing and using neuroimaging-based biomarkers for clinical purpo...
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Molecular neurobiological studies have yielded enormous amounts of valuable information about neuronal response mechanisms and their adaptive changes. However, in relation to addiction this information is of limited value because almost every cell function appears to be involved. Thus it tells us only that neurons adapt to 'addictive drugs' as they do to all sorts of other functional disturbanc...
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The mammalian ovary shows extensive variation mainly in relation to the interstitial tissue of the ovary, the so-called interstitial gland, and the degree of gonad regionalisation, which implies the existence of a cortex and a medulla. Three mammalian species, mouse, human, and mole, have been reviewed here as representative animal models for ovarian variability. Whereas the human ovary may be ...
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Robert Shulman belongs to a rare breed. On the one hand, he is a true pioneer of MRI, a technology that has galvanised cognitive neuroscience by allowing researchers to trace the flux of metabolic activity in the living brain under diverse experimental conditions. On the other, he is a staunch behaviourist who believes that terms like ‘attention’ and ‘working memory’ should be expunged from sci...
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ژورنال
عنوان ژورنال: The Review Review
سال: 2020
ISSN: 2690-0459
DOI: 10.33972/trr.67